Showing posts with label Covid Treatment. Show all posts
Showing posts with label Covid Treatment. Show all posts
Sunday, October 24, 2021
Wednesday, July 21, 2021
Saturday, July 17, 2021
Should I Prescribe Ivermectin for COVID? | Ivermectin Update 2021
Ivermectin
Last Updated: February 11, 2021
Ivermectin is a Food and Drug Administration (FDA)-approved antiparasitic drug that is used to treat several neglected tropical diseases, including onchocerciasis, helminthiases, and scabies.1 It is also being evaluated for its potential to reduce the rate of malaria transmission by killing mosquitoes that feed on treated humans and livestock.2 For these indications, ivermectin has been widely used and is generally well tolerated.1,3 Ivermectin is not approved by the FDA for the treatment of any viral infection.
Source of info:
FDA warns people not to take veterinary drugs to treat Covid-19
Instead of Ivermectin, take Covid Vaccine !
Thursday, March 25, 2021
Saturday, February 6, 2021
Doctors are Unravelling the Mystery of COVID 19
Doctors are Unravelling the Mystery of COVID 19
There is NEW evidence to suggest that COVID 19 is causing the body to make antibodies that attack itself.
COVID 19 is mysterious in a lot of ways, despite us already knowing a lot about it. Researchers & doctors are working hard to unravel the cause and effect of the interaction between the SARS-CoV-2 virus and the immune system. COVID causes several symptoms that may point to a phenomenon called autoimmunity as a potential cause of long COVID. This includes pulmonary fibrosis, meaning scarring of the lungs. Unfortunately, I’m seeing the same picture unfold in so many of my patients who have had COVID, with all this scarring in their lungs. And COVID can cause other issues, like brain changes, skin rashes, excessive blood clotting, inflamed blood vessels, and more.
Autoimmunity is when the immune system mounts an attack on its own healthy cells and tissues—mistaking them for foreign or virally infected cells. Under normal conditions, the immune system can discriminate between self and foreigners. Meaning it can differentiate between the body’s proteins and foreign antigens. But sometimes, in some people, the immune system can mistakenly identify its own proteins as foreign antigens, and it launches its attack on itself. When these autoantibodies react against self-antigens, the outcome can be inflammation and damage to tissues. This is what happens with autoimmune diseases like Type 1 diabetes, Graves' disease, multiple sclerosis. This is also what happens with idiopathic pulmonary fibrosis, where people develop scarring in their lungs, much in the same way that this happens with COVID 19. In fact, there are lots of auto-immune conditions that can cause scarring in the lungs, like lupus, rheumatoid arthritis, scleroderma, polymyositis, ankylosing spondylitis, and more—the evidence to support the role of autoantibodies as a cause of more severe COVID 19. The vast majority of people who get COVID 19 will have a disease isolated to the upper respiratory tract. But in 20 percent of people, the infection will go deep into the lung parenchyma and have the potential to cause more severe disease, meaning COVID pneumonia, which sometimes blossoms into ARDS.
Autoimmunity as a potential cause of more severe COVID 19 disease was brought up when autopsies. Cytokine storms are an overreaction by the immune system and are more systemic and short-term. In contrast, autoantibodies are more targeted and long-term. Dexamethasone, a corticosteroid, and the arthritis drugs tocilizumab and sarilumab have been used to modulate an overactive immune response. In a clinical trial, tocilizumab and sarilumab improved critically ill patients' outcomes on a ventilator in the intensive care unit.
A study at Rockefeller University in New York enrolled almost a thousand people with severe COVID 19. About 10% had antibodies that blocked the action of type 1 interferon molecules, a protein that helps the immune system fight pathogens. These autoantibodies were more common in men, who had 12.5% compared to 2.6% in women. This may explain why men are more likely to have severe disease. Thes are now screening study's researchers40,000 people to see what proportion of uninfected people carry these antibodies and their distribution by age, ancestry, and gender. This data will be compared to the distribution and percentage of each factor in people with severe COVID 19.
Researchers in another study supported the finding of increased autoantibodies in COVID patients. The antibodies they found were directed towards B cells, a type of immune cell that produces antibodies and interferon. Although the researchers noted no "COVID 19 specific" autoantibodies that distinguish COVID patients from uninfected controls, the levels of autoantibodies were correlated with known markers for inflammation. The correlations became more extreme as the disease worsened. These medications require careful timing to interrupt an overreactive immune system without interfering with a normal immune system fighting the COVID 19 infection. COVID 19 is often a biphasic illness with an initial phase, primarily respiratory symptoms caused by the virus and the immediate immune response, with innate immunity. Sometimes, it is followed by a secondary inflammatory phase.
There are two immune system arms, the non-specific innate immune system and the specific adaptive immune system. Whenever you are infected with a pathogen that is new to your immune system, you rely on the innate immune system to fight the pathogen. Interferons are essential to the innate response. Interferon-β is one of the first cytokines produced and drives the innate immune response in the lung. This connection illustrates the importance of the finding that SARS-CoV-2 may inhibit interferon activity in those who develop more severe COVID 19.
Doctor Mike Hansen, MD
Internal Medicine | Pulmonary Disease | Critical Care Medicine
Wednesday, January 27, 2021
Friday, January 22, 2021
COVID-19 treatment(s) given to Trump
8 drugs Trump has been given for his COVID-19 treatment
Monday, October 5th, 2020
Since President Donald Trump tested positive for COVID-19 Oct. 1, he has been given a variety of drugs intended to shorten his recovery time and ease symptoms.
Though no drug has been FDA approved to treat the virus, a handful have shown positive results in clinical trials. The president has been given drugs that are being tested in clinical trials and aren't available to the general public.
The eight drugs the president reportedly has been given:
Dexamethasone — President Trump was prescribed the steroid dexamethasone, a drug commonly used to treat asthma, rheumatoid arthritis and certain cancer, on Oct. 3. Sean Conley, DO, the president's physician, said the steroid was given to him in response to his blood oxygen levels dropping twice to 93 percent, according to STAT.
The steroid is typically recommended for hospitalized patients who need oxygen or are on ventilators. A study released in June showed that dexamethasone reduced deaths by one-third for those who had been sick for more than a week and were on mechanical ventilators, but had no impact on patients receiving no respiratory support. The study suggested that the drug may do more harm than good for patients with milder COVID-19 cases, since steroids hamper the body's immune system.
The drug is typically given to patients with severe COVID-19 to prevent an immune system overreaction. Some experts called it a "major breakthrough" for COVID-19 treatment, as it was the first drug shown to improve survival rates.
Remdesivir — President Trump was given his first dose of remdesivir Oct. 2, and he will be given a five-day course, CNN reported. Remdesivir, made by Gilead (who gave it the brand name of Veklury), was granted emergency use authorization by the FDA on May 1 after a study showed it caused a 31 percent faster recovery time compared to a placebo.
Remdesivir is an intravenous drug that works by targeting the system coronaviruses use to replicate themselves. It has been previously tested for Ebola, but hasn't been officially approved in any country. The FDA expanded its emergency use authorization for remdesivir Aug. 28, allowing it to be used on all hospitalized patients. It had previously only been authorized for those on ventilators or with low blood oxygen levels.
Regeneron's monoclonal antibody — On Oct. 2, the White House released a letter saying the president received a single 8-gram dose of Regeneron's monoclonal antibody cocktail, called REGN-COV2, the highest dose of the drug being tested in late-stage clinical trials, according to Politico.
Regeneron said in a Sept. 29 news release that a high dose of the drug caused the level of the virus to decrease in patients in an early clinical trial, indicating it may help COVID-19 patients recover faster. The trial seemed to show the drug had a bigger effect on patients who were infected with the virus but hadn't created high levels of their own antibodies against the virus. The drug uses synthetic versions of the antibodies patients' bodies create when they recover from a disease. In July, Regeneron received $450 million from Operation Warp Speed, the White House's task force to expedite COVID-19 vaccine development, to manufacture thousands of doses of the drug.
Regeneron CEO Leonard Schleifer, MD, PhD, told The New York Times that President Trump's medical staff reached out to the company for permission to use the drug, and that it was cleared with the FDA. Mr. Schleifer has known the president casually for many years and is a member of his golf club in Westchester County, N.Y., according to the Times.
Zinc — President Trump also has been given zinc, according to the Times, which helps the immune system fight outside bacteria and viruses. Zinc is an essential mineral that is naturally present in some foods and is available as a dietary supplement. There is no evidence that zinc helps fight COVID-19, and the FDA has issued warning letters to some companies that have tried to claim there's a link between zinc products and reduced risk of COVID-19.
Vitamin D — President Trump has been given vitamin D, the Times reported, which is good for bone health. There is no evidence vitamin D directly reduces the risk of COVID-19, and the FDA has sent warning letters to companies trying to sell vitamin D products as COVID-19 treatments. Vitamin D can also help reduce inflammation, according to the National Institutes of Health.
Famotidine — The generic name for Pepcid, famotidine is commonly used to treat ulcers, heartburn, indigestion and reduces the amount of acid in the stomach. A clinical trial testing the drug in hospitalized COVID-19 patients in New York wasn't able to recruit enough patients to properly evaluate its impact, according to Science.
Melatonin — Commonly used to treat insomnia, some studies have suggested that melatonin could also help COVID-19 patients with diabetes and obesity, according to CNN.
"The ability of melatonin to decrease viral infections in obese and diabetic patients is attributed to its characterists, such as potent antioxidant effects, improving the endogenous antioxidant system, immunomodulatory, and the strong anti-inflammatory capability," according to researchers from Mansoura University in Egypt.
A health summary for President Trump released in June showed that he was obese, at 244 pounds, the Times reported.
Aspirin — Commonly given to older patients to prevent heart disease, aspirin is also a popular painkiller. It can reduce the risk of blood-clotting, and evidence has shown COVID-19 can trigger blood clots in some patients. The president has mild heart disease, the Times reported.
Sunday, December 13, 2020
Long Covid: When coronavirus symptoms don't go away | DW News
- Covid19 Health Center / TESTING Center
- Johns Hopkins University (Map and Statistic)
- ncov2019.live (Map and Statistic)
- CDC Centers for Disease Control and Prevention
- WHO World Health Organization
- Hotline KBRI - KJRI
- KBRI Washington DC: +1 202 569 7996
- KJRI Chicago: +1 312 547 9114
- KJRI Houston: +1 346 932 7284
- KJRI Los Angeles: +1 213 590 8095
- KJRI New York: +1 347 806 9279
- KJRI San Francisco: +1 415 875 0793
Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. ...
Coronavirus Update 118: AstraZeneca DNA COVID 19 Vaccine Explained (vs. Pfizer / BioNTech, Moderna)
- Covid19 Health Center / TESTING Center
- Johns Hopkins University (Map and Statistic)
- ncov2019.live (Map and Statistic)
- CDC Centers for Disease Control and Prevention
- WHO World Health Organization
- Hotline KBRI - KJRI
- KBRI Washington DC: +1 202 569 7996
- KJRI Chicago: +1 312 547 9114
- KJRI Houston: +1 346 932 7284
- KJRI Los Angeles: +1 213 590 8095
- KJRI New York: +1 347 806 9279
- KJRI San Francisco: +1 415 875 0793
Saturday, December 12, 2020
Vitamin D and COVID 19: The Evidence for Prevention and Treatment of Cor...
If you choose to take vitamin D supplements, 10 micrograms a day will be enough for most people. Do not take more than 100 micrograms (4,000 IU) of vitamin D a day as it could be harmful. This applies to adults, including pregnant and breastfeeding women and the elderly, and children aged 11 to 17 years.
Source: https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-d/
- Covid19 Health Center / TESTING Center
- Johns Hopkins University (Map and Statistic)
- ncov2019.live (Map and Statistic)
- CDC Centers for Disease Control and Prevention
- WHO World Health Organization
- Hotline KBRI - KJRI
- KBRI Washington DC: +1 202 569 7996
- KJRI Chicago: +1 312 547 9114
- KJRI Houston: +1 346 932 7284
- KJRI Los Angeles: +1 213 590 8095
- KJRI New York: +1 347 806 9279
- KJRI San Francisco: +1 415 875 0793
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